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Every comprehensive high school in SISD offers an advanced academics academy to give real-world experiences and specialized classes and training. Students in these academies have the opportunity to earn dual credit and participate in intensive internships.
- Aztec Architectural Academy and International Baccalaureate Program at El Dorado High School - Architecture, International Studies
- Health Professions Academy at Socorro High School – Medical Field
- Libertas Academy at Americas High School - Judicial System, Government, Public Administration
- Sparta Business Academy at Pebble Hills High School - Business and Finance
- Synergi4 at Montwood High School – Science, Technology, Engineering and Math
- School of Advanced Technology Applications at Eastlake High School – Computer Science